Incubator INCO108
For cell cultivation and especially for in-vitro fertilization, the precision and reliability of CO2 incubators are of crucial importance. During cultivation, the slightest deviation in the CO2 atmosphere, temperature or humidity can influence cell development. For this reason, Memmert has subjected its CO2 incubators to a comprehensive evaluation process for their recognition as medical devices.
The classification as class IIa medical device confirms that all Memmert CO2 incubators INCOmed comply with the basic safety requirements of the European Medical Devices Directive 93/42/EEC. Memmert’s incubators feature a unique sterilization cycle because simply disinfecting the chamber is not reliable. To prevent cross-contamination, the entire incubator chamber, including the ventilation system, shelves/grids can be sterilized with a 4-hour program at 160ºC. (only available for IN/IFplus models) Ensuring sterility between loads has never been easier.
- Comfort Module:Two gas connections with quick release connectors, automatic switch-over between gas bottles (a combination of the Comfort Module and the O2 Module is not possible since the N2 introduction takes place via a second gas bottle connection)
- Hygiene Module: Electropolished, seamless laser-welded chamber
- Communication Module: USB interface, "Celsius" standard software for programming and protocol logging, ring memory, printer port
- CO2 Module: Extended CO2 range from 0% to 20%
- O2Module: Control of oxygen concentration by introducing nitrogen, adjustment range from 1% to 20% O2 (combination of Comfort Module or Premium Module and O2 Module not possible, since N2 is introduced via a second gas bottle connection). For applications with a set O2 value of less than 10%, the Humidity Module is highly recommended
- Premium Module: Includes Comfort, Hygiene, Communication and CO2modules
- Humidity Module: Active microprocessor humidification and dehumidification control (40% - 97% rh). Recommended for applications with set O2 values of less than 10% (Available only with CO2 Incubators)
High-end functions for the protection of cell cultures, bacteria cultures or tissue cultures.
Those who can control the temperature with the highest precision can also redefine precision time and time again. The control system of the Memmert CO2 incubator ICOmed is so finely tuned that the appliance reaches the setpoint temperature very quickly and without temperature overshoots. Alarm notifications to your mobile phone guarantee the safety of the chamber load, and the battery-buffered ControlCOCKPIT ensures continuous CO2 control even when there is a power failure. Ideal hygiene is a given too: rounded edges enable easy and thorough cleaning, the interior can be sterilised within 60 minutes at 180 °C.
- Temperature range up to +50 °C
- 4 model sizes (with a chamber volume of 56 to 241 litres)
- Fail-safe, FDA-compliant logging of temperature, CO2, O2 humidity, open door time data
- Battery-buffered ControlCOCKPIT: The operating display, logging and CO2 control are fully functional even during a power failure
- Visual and acoustic alarm as well as alarm notification to mobile phones if the individually adjustable temperature, CO2, O2, or humidity ranges are exceeded
- Active humidity control
- The interior chamber, including all installations and sensors, can be sterilised at +180 °C in a 60-minute programme
Intended use of ICOmed as medical device
Especially for in-vitro fertilization, the precision and reliability of the CO2 incubator are of crucial importance, as the slightest deviation in the CO2 atmosphere, temperature or humidity content during cultivation can already affect cell development. Memmert therefore subjected its CO2 incubator ICOmed to a comprehensive medical device evaluation. Every Memmert CO2 incubator ICOmed is classified as a Class IIa medical device for the in vitro fertilisation (IVF) as well as biosynthesis. The CE label on the appliances includes the mark 0197, denoting TRLP – TÜV Rheinland as the notified body.
Minimising vaporisation and condensation
Active humidity control ensures short recovery times after the door has been opened and minimises vaporisation in the interior. Together with the heating of the interior from all six sides and the heated inner glass door, it offers maximum protection for cell and tissue cultures and avoids the dangerous formation of condensation. The turbulence-free chamber ventilation ensures a constant and uniform atmosphere.
A Memmert CO2 incubator offers unique advantages
- User-friendly, intuitive operating concept
- Almost exclusive use of high-quality, corrosion-resistant and easily cleanable stainless steel for the inner chamber and housing
- Precise and homogenous temperature control thanks to a product-specific heating concept
- A wide range of options for programming and documentation using interfaces, integrated data loggers and the AtmoCONTROL software
- 3 years guarantee worldwide
Unrivalled user friendliness
All parameters can be set easily and intuitively both with the operating display and the ControlCOCKPIT or the AtmoCONTROL software. The shutter box can be opened, allowing fast access to controls. Maintenance is possible even if the appliances are stacked. The incubator ICOmed has USB and Ethernet connections as well as a data logger with a ten-year storage capacity. Data can be read and programmes can be uploaded by remote access. Numerous features of the CO2 incubator ICOmed don’t let anything open to be desired:
- Two gas connections with quick release connectors for automatic switch-over of gas bottles
- Electropolished, seamlessly welded chamber
- Electronic control for active humidification and dehumidification (40 to 97 % rh)
- Control of oxygen concentration by introducing nitrogen, adjustment range from 1 % to 20 % O2
Stainless Steel Construction
The inner chamber of the INCO consists exclusively of high-grade, fully recyclable hygienic stainless steel 1.4301 (ASTM 304). The additional electro-polishing of the chamber, seamlessly welded by laser, ensures particularly smooth surfaces and therefore a reduction in contamination risk (available with optional Hygiene Module). The outer casing is made mainly from sturdy textured stainless steel and is in accord with Memmert's holistic quality philosophy.
Uniformity Inside the Chamber
Chamber heating from all six sides, together with electronic humidity control, is responsible for the optimal temperature and humidity distribution. An aluminum heat-conducting jacket helps to ensure the homogeneity inside the chamber and in addition serves as heat store in case of a temporary supply outage. Despite the appreciably higher density of CO2 compared with air, the turbulence-free chamber ventilation provides a uniformly homogeneous atmosphere. Memmert special: the all-round heating is located below deep-drawn ribs which carry the non-tipping stainless steel shelves and at the same time ensure optimal and particularly gentle heat transfer to the incubator load.
Short Recovery Times Due to Active Humidity Control
The INCOmed standard model features a humidity limiting system to reduce water tray generated maximum relative humidity inside the chamber from 97% to 88%. To achieve and increase in usable volume, optimum hygiene and short recovery times after opening the door, the optional Humidity Module offers an active humidification system with an adjustment range of 40% to 97% rh can be integrated, introducing sterile hot steam into the air stream.
Germ-Free Through Sterilization, Because Disinfection is Not Sufficient!
Hygiene is the most important factor for highly-sensitive applications with an organic chamber load. To prevent appliance-related cross-contamination, the chamber, including the ventilation system, the water trays and all the sensors can be sterilized in a 4-hour program at 160°C. (in accordance with DIN 12 880: 2007-05). To prevent unintentional start in the CO2 Incubators, the automatic sterilization cycle can only be activated via the MEMMERT STERICard.
Applications:
- Used in the laboratory and the industry: culture medium tissue or cells, in vitro fertilization, gene expression
Technical Data:
- Volume: 108 liters
- Interior dimension: width 560 x height 480 x depth 400 mm
- Exterior dimension: width 710 x height 778 x depth 550 mm
- Stainless steel water dishes: 01
- Perforated stainless steel shelves: 02
- Incubatory for culture in medical, life sciences, environmental technology, microbial science research, virology, microbiology, biotechnology, zoology.
- Uniform atmosphere and temperature distribution owing to enclosed non-turbulent ventilation system in working chamber.
- Adaptive, fuzzy-supported multifunctional digital microprocessor PID-controller
- Integral fault diagnostics for temperature, CO2 and humidity limit control.
- 2 Pt100 sensors Class A in 4-wire-circuit, mutually monitoring and taking over the performance at the same temperature value
- Temperature range: from +20 to +50oC
- Working temperature range: +8oC above ambient temperature up to +50oC
- Temperature fluctuations with time (to DIN 12 880: 2007-05): ≤ ± 0.10C
- Temperature variation in chamber at +37 °C (to DIN 12 880: 2007-05): ≤ ± 0.30C
- Resolution of temperature : 0.1°C
- STERICard for automatic chamber sterilisation cycle 4 h at +160 °C (not for sterilising the load)
- Digital electronic CO2 control with autozero, NDIR system, with auto-diagnostic system and acoustic fault indication, barometric pressure compensation.
- Setting accuracy: 0.1% CO2
- Adjustment range CO2: 0 – 10%
- Humidity sensor
- Adjustable humidity limit control (88 – 97 %) incl. digital indication and auto-diagnostic system with visual and acoustic fault indication (air supply via sterile fi lter) ensures rapid reaching of set humidity and short recovery times while avoiding condensate formation.
- Digital 7-day programme timer with real time clock, precise minute setting. Digital display of all set parameters, such a temperature, weekdays, time, CO2, humidity and set-up values - language to be chosen via set-up.
- CO2-supply via sterile filter
- Intrinsic adjustment of altitude above sea level
- CO2-supply interruption upon door opening
- Calibration facility through controller for three freely selectable temperature values, 2-point-calibration for humidity: 20 and 90%, 3-point calibration for CO2: 5%, 7%, 10%. Auto-zero-function of NDIR CO2-sensor after every sterilisation and cyclically every 24 h.
- Setting of language for dialogue and display DE / EN / ES / FR / IT
- Programme stored in case of power failure
- USB-interface incl. Memmert software "Celsius" for programming and documentation.
- 100% safety for air (100% AtmoSAFE).
- Large-area multi-function heating system on four sides with additional door and back heating to avoid condensation
- Incl. works calibration certificate for +37°C.
- Humidity supply with distilled water from external tank by self-priming pump.
- Humidification by hot steam generator.
- Alarm by audible and visual.
- Overtemperature monitor TWW, protection class 3.1 or adjustable temperature limiter TWB, protection class 2, selectable on display.
- With audible and visual alarm in case of over-/under temperature or CO2, open door and empty gas cylinder.
- Additionally integrated over- and undertemperature monitor "ASF", automatically following the setpoint value at a preset tolerance range; alarm in case of over- or undertemperature, heating is switched off in case of overtemperature.
- Mechanical temperature limiter TB, protection class 1 according to DIN 12 880 to switch off the heating approx. 10°C above nominal temperature.
- Textured Stainless Steel Casing.
- Fully insulated stainless steel door with 2-point locking (compression door lock), lockable.
- Inner glass door with opening (8 mm Ø) to take gas sample.
- Rear zinc-plated steel.
- Easy-to-clean interior, made of stainless steel, reinforced by deep drawn ribbing, material 1.4301 (ASTM 304), hermetically welded.
- Voltage / Power Rating: 230 V (+/- 10%), 50/60 Hz / approx. 1000 W.
Including:
+ Stainless steel water dishes
+ Stainless steel shelves
+ Works calibration certificate of manufacture
+ STERICard
+ Operators manual.
Options:
- Comfort module: two gas connections with quick release connectors, automatic switch-over of gas cylinders (order no: T1)
- Hygiene module: electropolished interior, seamlessly welded by laser (order no: T2)
- Communication module: USB interface, “Celsius” standard software for programming and documentation, ring memory, printer interface (order no: T3)
- CO2 module: extended CO2 range from 0 to 20 % (order no: T4)
- Premium module: includes Comfort, Hygiene, Communication and CO2 module (order no: T5)
- Humidity module: active microprocessor control for humidifying and dehumidifying (40 – 97 % rh), incl. digital indication and auto-diagnostic system ensures even more rapid reaching of set humidity and very short recovery times while avoiding condensate formation; recommended for applications with set O2 values of less than 10 %. Humidity supply with distilled water (from an external tank) by a self-priming pump (standard humidity limit control and water dishes are omitted)( order no: K7)
- O2 module: control of oxygen concentration by N2 inlet; adjustment range 1 % up to 20 % O2; setting accuracy 0,1 %. For applications with a set O2-value of less than 10 %, the humidity module is highly recommended (order no: T6)