Intelligently Designed to be Flexible and Reliable
The BX63 is a motorized microscope developed in response to the requests of hundreds of researchers and microscope users. With a simple touch, users can operate the microscope quickly through the detachable and freely positional U-MCZ controller or by means of a computer with cellSens imaging software*. All data captured via controlling the microscope through the touch panel or U-MCZ controller are continually fed back through cellSens, providing the freedom to operate the microscope in the most convenient manner for the user. From image capture to report creation, Olympus cellSens personalizes researchers’ individual operational environments in accordance with individual researcher workflows. * cellSens software is not for clinical diagnostic use
Stability for Improved Imaging Reliability
The BX63 is focused by motorizing the nosepiece in the Z-axis (possible due to the infinity-corrected optics) and fixing the stage to the rest of the frame at two additional points, making it extremely stable. In addition to this stability, the motorized nosepiece Z-drive is very accurate, enabling highly precise Z-stack capture and subsequent deconvolution.
Precision Motorized Focus and Field Diaphragm
Motorizing the nosepiece has the advantage that the objective can be changed using either the remote control handset or the PC software control. This makes imaging far more efficient, freeing the user up to perform other tasks. Also, the more advanced imaging techniques may require the use of multiple magnifications and, with a motorized nosepiece and cellSens software, the whole process can be automated. A further benefit is that the correct objective is selected every time and the magnification is recorded with each image.
Advanced Sensitivity in Fluorescence Imaging
Higher signal-to-noise ratio (S/N) produces fluorescence images with bright colors and dark background, that’s why Olympus has pushed the boundaries of S/N with improved fluorescence detection capacity. Uniform illumination and detection is achieved through the use of high transmission objectives, mirror units, and the incorporation of a fly-eye lens system.
Fluorescence Illuminators with Fly-eye Lens System
It is important to ensure that the field of view is illuminated evenly. The nature of fluorescence illumination makes this a difficult task, but Olympus has developed a new solution with its fluorescence illumination concept, which incorporates a fly-eye lens system. As a result of this advance, not only are users assured of flawlessly homogeneous illumination across the entire wavelength spectrum, but they also have the benefit of much simpler burner alignment.
Integrated Flexibility in Fluorescence
The Olympus 8-position fluorescence illuminator allows greater flexibility for a wide variety of fluorescence specimens with its easily exchangeable mirror units. Observations are accelerated further through the reduced need to replace mirror units for multicolor or FISH applications.
cellSens Capture Multidimensional Images
The Process Manager makes it easy to capture multicolored and multidimensional images with just acouple of clicks.
Fluorescence Mirror Units with Advanced Coatings and Stray Light Reduction
The UIS2 fluorescent mirror cube range is optimized for fluorescence imaging. High quality coatings used on the mirror cubes provide excellent transmission and steep cut-off slopes, while the interior surfaces eliminate over 99 % of stray light, ensuring the highest sensitivity and best color separation. The mirror cubes can be exchanged quickly and easily without tools.
High Transmission with Reduced Autofluorescence
At the heart of any light microscope is the quality of the optical system. Olympus UIS2 optical components have been developed to provide the perfect optical system, setting new standards in precision and clarity. The high NA objectives lenses are optimally corrected for chromatic aberrations and deliver high resolution, with even the faintest of signals being collected. By using carefully selected raw materials for glass, and applying advanced UW multi-coatings technology, Olympus has reduced objective autofluorescence and significantly improved the S/N ratio. UW multi-coatings also yields a flat, high transmission over a wide wavelength range, ensuring high performance in research tasks using different types of fluorochromes.
Condenser Designed to Reduce Back-Reflections
The motorized universal condenser is designed to reduce back-reflections and autofluorescence by swinging its top lens out, automatically closing its diaphragm to the minimum, and locating the wheel in between two positions in fluorescence imaging.
Low Autofluorescence Immersion Oil
The ability to reduce auto-fluorescence normally associated with immersion oil makes this product well suited for fluorescence microscopy. Reduced noise (auto-fluorescence) results in an increased signal-to-noise ratio for better fluorescent observation. Temporal change of auto-fluorescence is less. Especially useful in quantitative observation of single molecule fluorescence, which is easily affected by noise. Resistance to crystallization allows it to be used over long periods of time. The refraction index is the same as other Olympus products, assuring easy integration with your existing microscopy system.
World-Renowned Optical Performance
At the microscope level, biological samples tend not to possess inherent contrast, such as color variations, when using standard brightfield illumination. As a result, a number of different ways of generating contrast have been developed. These can be split into two parts: optical contrast methods and sample contrast methods. Whatever the source of contrast, the Olympus BX3 range and UIS2 optical components perform flawlessly, providing sharp and clear images in any contrast method.
Efficient Design for Easy Operation
Straining to view live images while adjusting the microscope is not necessary. With the BX63 and Olympus cellSens software*, flexibility is provided to place the touch panel and U-MCZ remote microscope controller anywhere on the bench, enabling quick and efficient image focusing and framing with the U-MCZ positioned close to the monitor. Simple and quick switching between observation methods and magnifications is provided by the cellSens Process Manager. This automates multicolor, multipoint and other imaging methods from settings entered through the touch panel or directly into cellSens. After acquisition, image processing, measurement and analysis is completed through the Olympus cellSens software. * cellSens software is not for clinical diagnostic use
Motorized Attenuator Wheel for Lighting Control
The Olympus BX63 has a motorized ND filter wheel for fluorescence and transmitted light intensity adjustments. Special adapters are required for mounting (U-LHEAD for fluorescence, and U-LH100ADP for transmitted light).
Motorized Nosepiece with Seven Positions
This revolving nosepiece (U-D7REA) allows simultaneous attachment of seven objectives. It is especially suitable for continuous observations from low to high magnifications and combining specific objectives, such as polarized light observations.
Motorized Universal Condenser
By integrating with designated optical components, the motorized universal condenser (BX3-UCD8A) accommodates various kinds of transmitted light observation, from brightfield to differential interference contrast and phase contrast.
Ultrasonic Stage for Precise Movement
The ultrasonic stage (BX3-SSU) delivers high-precision XY control. The XY controller can be mounted on the controller/U-MCZ for the BX63 and worked like conventional stage handles.
Motorized Panoramic Imaging
With cellSens Dimension software, wide area imaging using a motorized stage is fully automated with the optional Multiposition solution. When combined with a motorized Z, this function can correct for the effects of sample distortion and tilting.
Touch Panel Controller for Powering All Operations
The BX63 can switch between different observation methods and magnifications with one touch. The controller offers the choice of a Guidance Mode enabling navigation of procedures currently in use, and the Full Operations Mode that provides access to an entire range of settings - keep full control close at hand for prompt view of microscope system status. Furthermore, multiple observation points and conditions can be saved in advance, enabling rapid recall and reproduction of imaging conditions used by other researchers.
U-MCZ Controller for Rapid and Familiar Operation
The U-MCZ controller can be detached from the microscope frame and positioned wherever required. When used in combination with the XY controller, provided with the ultrasonic stage, it delivers user-friendly focusing and framing operations that mimic a conventional microscope while live images in the Olympus cellSens software are kept clearly in view. Controls are also conveniently located to enable switching between different observation methods, objectives, and mirror units while retaining the ability to simultaneously select intensity adjustments or image capture.
Task Management with Less Effort
With microscope optics pushing the boundaries of resolution at all magnifications and new microscope design enabling techniques, it is important to be able to efficiently capture and process the images produced. In addition, an increasing number of researchers are using microscopy and it is, therefore, essential that imaging and analysis are both flexible and user-centric.
Olympus cellSens for Efficient Imaging
Capture multi-color, time lapse, and z-stack images with ease. Just select the appropriate capture button, add relevant parameters, and click "Start". The Process Manager or Graphical Experiment Manager(GEM) make it easy to capture multidimensional image. The GEM function allows experiments to be designed with even greater versatility. Furthermore, image acquisition is available for up to 6 dimensions (XYZTλ multipoint).
Digital Imaging to Fulfill Diverse Needs
The versatile BX63 system is more than a microscope and can easily be tailored to a sophisticated imaging system for any application. From advanced cutting edge research to optimal stand-alone models for conferencing. Our full line of digital cameras and cellSens imaging software ensure e.g. the capture of fluorescence images with highest S/N ratio.